Skin lightening products form a major segment of cosmetic products worldwide and carry with them the promise of flawless skin free from age spots, blemishes and scars. Whatever the color of the skin, it is susceptible to damage due to environmental agents, physiological changes and psychological factors. 

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Aging is attributed to the effects of collective damage to connective tissues, that overpowers the body's natural ability to repair them. The perceptible signs of skin aging include discoloration, wrinkles, and texture loss. These effects results from structural and metabolic changes effected by biochemical reactions in the connective tissues ,that are accelerated by free radicals.

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Oral care has received greater attention in the past decade, particularly in view of increasing scientific evidence that links poor oral health with the incidence of chronic diseases, such as cardiovascular disease. In general, oral care targets prevention of decay, as well as preservation of tooth and gum health.

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Cosmeceuticals, "performance cosmetics", "functional cosmetics", "dermoceuticals", "active cosmetics".... these are the buzz words in twenty first century personal care. The revolution they triggered is apparent from the fact that cosmetics are no longer visualized as products that cover up or camouflage imperfections in personal appearance. 

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Skin, as a protective organ of the body, is subject to many factors from within the body and from the outside environment that constantly challenge its integrity and protective functions. Diverse factors such as ultraviolet light (UV), atmospheric pollution , increased atmospheric ozone, wounds, infections

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The quest for novel topical delivery systems for bioactives ,with emphasis on "natural" and "safe", is an area of dynamic research in the pharmaceutical, cosmetics and nutritional fields. Tetrahyropiperine is a natural topical premeation enhancer for active compounds.

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Aging results from cumulative damage to tissues that overwhelm the body’s natural ability to repair them. The tell-tale signs of aging on the skin include discoloration, wrinkles, and texture loss. These effects result from structural and metabolic changes effected by biochemical reactions in the connective tissues that are accelerated by free radicals. 

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Skin and digestive tract are the largest organs of our body. These are also some of the oldest structures developed in the evolutionary process to provide the organism with essential information about the outside world, largely by delivering nutrients from the outside world.

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For centuries humans have been aware of the subtle influence of seasonal changes on their physical and emotional well-being. The ancient systems of medicine therefore addressed the specific needs of human body in its process of adapting of seasonal changes as a means to maintain the state of good health and prevent disease.

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The quest for medications and cosmetic measures to combat acne continues to be a major research and development initiative in the pharmaceutical and personal care industries. Acne is reported to affect about 17 million individuals in the United States alone1. 

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