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Peer-Reviewed Clinical Trial Shows Sabinsa’s Sabeet® Improves Muscle Quality and Neuromuscular Performance in Postmenopausal Women

Press Release

Sabinsa announces the publication of a new randomized clinical trial demonstrating that long-term supplementation with Sabeet®, a nitrate-rich beetroot extract, significantly improves key markers of muscle quality and neuromuscular performance in postmenopausal women.

The study, titled “Long-Term Beetroot Extract Supplementation Improves Morphological Muscle Quality and Rate of Force Development in Postmenopausal Women: A Randomized Clinical Trial,” was published in the peer-reviewed journal Nutrients (March 2026), with Sabinsa’s Global CEO and Managing Director, Shaheen Majeed, serving as a co-author.

Conducted using a randomized, double-blind, placebo-controlled design, the 12-week trial evaluated the effects of daily supplementation with a standardized nitrate-rich beetroot extract (548 mg nitrate/day) in postmenopausal women aged 60 to 85. Participants were assessed for muscle quality, strength, rate of force development (RFD), and circulating nitrate and nitrite levels at baseline, 8 weeks, and 12 weeks.

The results demonstrated statistically significant improvements in morphological muscle quality, as measured by ultrasound echo intensity, in the Sabeet® group compared to placebo. In parallel, participants receiving the nitrate-rich extract also experienced marked increases in early- and late-phase RFD, indicating enhanced neuromuscular performance and the ability to generate force more rapidly, a key factor in balance recovery and fall prevention.

“Sabeet® was specifically developed to deliver standardized, meaningful levels of dietary nitrate, and this 12-week trial shows that commitment translating into real, tangible benefits for women navigating the muscle health challenges of menopause,” said Shaheen Majeed, Global CEO and Managing Director of Sabinsa. “The improvements observed in both muscle composition and neuromuscular speed, mediated by enhanced nitric oxide bioavailability, speak to the depth of this ingredient’s potential for healthy aging, and are particularly relevant for supporting mobility, balance, and overall functional independence in postmenopausal women. At Sabinsa, we believe that evidence like this is what separates a clinically meaningful ingredient from a commodity.”

The study also confirmed significant increases in circulating nitrate and nitrite levels in the Sabeet® group, reinforcing the role of nitrate supplementation in enhancing nitric oxide bioavailability, a key mediator of vascular function, muscle perfusion, and contractile efficiency. These biochemical improvements were sustained through both the 8-week and 12-week assessments, demonstrating the durability of the effect.

Researchers concluded that sustained supplementation with nitrate-rich beetroot extract offers a practical nutritional strategy to address age-related declines in muscle quality and neuromuscular function. The findings are particularly significant given the increased risk of sarcopenia, reduced mobility, and falls in postmenopausal populations.

Sabinsa’s involvement in this research reflects its longstanding commitment to advancing clinically substantiated, science-first ingredients that address the real health challenges of aging.