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Sabinsa Corporation Granted Patent for Tetrahydrocurcuminoids

Press Release

The patent describes a mixture of tetrahydrocurcuminoids, which can be used for regulating random, intracellular protein crosslinking and to optimize skin cell electric potential. Tetrahydrocurcuminoids consist of tetrahydrocurcumin (the main constituent), terahydrodemethoxycurcumin and tetrahydrobisdemethoxycurcumin. The Bioprotectant® and Crossregulin® composition of tetrahydrocurcuminoids was found to be particularly effective in tyrosinase inhibition, and in affording protection to the skin against UVB radiation and chemical, physical and biological irritants. These benefits are attributed to the superior properties of the composition described by inventors as Crossregulin® in regulating the posttranslational modification and crosslinking of intracellular proteins to deliver the desired nutraceutical and cosmeceutical benefits.

Tetrahydrocurcuminoids (THC) are colorfree compounds derived from curcuminoids, the yellow natural phenolic antioxidant compounds extracted from turmeric roots (Curcuma longa, family: Zingiberaceae). Curcuminoids prevent free radical formation and scavenge free radicals in biological systems, which amounts to the "Bioprotectant" mechanism that protects the integrity of living cells. The antioxidant effects of curcuminoids combined with their known inhibitory effects on cyclooxygenase 2 (COX2) render them useful as ingredients in antiaging formulations and in topical formulations designed to maintain general skin health and integrity. THC have also been found to inhibit the activity of tyrosinase, an enzyme that participates in melanogenesis, thereby preventing melanin formation with resultant lightening of the skin tone. These biological properties of the THC combined with their lack of yellow color, render them useful in achromatic food and cosmetic applications

Sabinsa Corporation is an application oriented manufacturing and marketing company, which manufactures and supplies Phytonutrients, herbal extracts and specialty fine chemicals used in nutritional supplements, cosmetics, pharmaceuticals, and food products. Sabinsa distinguishes itself by its extensive research support for its customers and products, and the scientific credentials of its key technical staff.

Contact: Dr. Vladimir Badmaev
Tel: 7327771111;
Fax: 7327771443
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